James Cook Rushing Odds & Player Props This Week

Buffalo Bills running back James Cook III (4) celebrates his touchdown during an NFL football game between the Carolina Panthers and the Buffalo Bills on Sunday, Oct. 26, 2025, in Charlotte, N.C.
(AP Photo/Jacob Kupferman)

The Divisional Round of the AFC playoffs is here, and the Denver Broncos will host the Buffalo Bills and their star running back, James Cook. 

All postseason, football betting on Cooks’ player props are available at BetMGM, along with NFL futures odds like who will win Super Bowl 60, the Super Bowl MVP, and more. This includes the Bills’ Super Bowl odds, currently third at +550. 

Below are five of the most notable prop bets for Cook this week, along with my predictions.

Best James Cook Prop Bets vs. Broncos

In the Wild Card round, Cook ran 15 times for 46 yards and caught two passes for five. It was a down performance, and something I expected against the league’s best run defence, the Jacksonville Jaguars. 

This week, he draws the league’s second-best run defence — the Broncos allow 91.1 rushing yards per game. Of that 91.1 rushing yards allowed per game, 71.8 are to running backs.

Cook’s rushing yards total in this game is 77.5. The Broncos have only allowed one running back to exceed this total, and that was the Indianapolis Colts’ Jonathan Taylor in Week 2, who ran for 165 yards on 25 carries. 

Since Week 10, the most they’ve allowed is 73, which the Green Bay Packers’ Josh Jacobs had in Week 15. 

As for the receiving game, the Broncos allow the fewest receptions per game to running backs at 2.94. 

I predict that this will be another week of taking Cooks’ unders. 

James Cook Rushing Yards Odds

OverUnder
77.5 (-118)77.5 (-110)

James Cook Rushing Attempts Odds

OverUnder
18.5 (+100)18.5 (-135)

James Cook to Score a Touchdown Odds

Odds
-118

James Cook Receiving Yards Odds

OverUnder
15.5 (-115)15.5 (-115)

James Cook Receptions Over/Under Odds

OverUnder
2.5 (+105)2.5 (-140)

The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.

About the Author Read More @richardjanvrin

Richard Janvrin is a content writer for BetMGM. His work is also published at sites like Forbes, WSN, Gambling.com, Legal Sports Report, and more. He has a bachelor's degree from the University of New Hampshire.

Richard Janvrin is a content writer for BetMGM. His work is also published at sites like Forbes, WSN, Gambling.com, Legal Sports Report, and more. He has a bachelor's degree from the University of New Hampshire.